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Its primary uses as a dietary supplement include support for the liver and antioxidant effects

Respiration traces were started by adding 10 mM glutamate/malate as respiratory substrate for complex I

At the protein level, PTDSS1 inhibitors significantly suppressed the expression of ferroptosis suppressor proteins (including SLC3A2, GCLM, GCLC, and GPX4), while RSL3 only had a significant effect on GPX4 and had a minor impact on other proteins

The insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein 1 phosphorylation bifurcates at a rapamycin-sensitive point immediately upstream of p70s6k