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doi: 10.1182/blood-2012-04-422527 79 ZhouJLiuYWuJ

61 774778 Shan C and Sun H 2018 Jasmonic acid-induced NO activates MEK1/2 in regulating the metabolism of ascorbate and glutathione in maize leaves

This can sometimes lead to what's known as a Herxheimer reaction, or a 'healing crisis.' As toxins are mobilized from tissues and flushed out of the body, they can cause temporary symptoms like headaches, fatigue, skin rashes, andyou guessed itdigestive upset

These metabolic effects of MT-II are mediated by binding to MC3R and MC4R, providing another intriguing use case for researchers interested in evaluating the MT-II peptide [24]