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Castillo-Jimenez M

Frozen grids were imaged using a Titan Krios microscope (Thermo Fisher Scientific) operated at 300 kV and equipped with an X-FEG electron source and a K3 direct electron detector (Gatan) with a Bioquantum post-column energy filter operated in zero-loss imaging mode with a 20 eV slit width

ADA1 is the most common form and is crucial for immune system function, while ADA2 is involved in various biological processes, including inflammation and cell differentiation. In autism, there is a higher prevalence of ADA2 which has about 80% the functional capacity of ADA1 which can lead to higher levels of adenosine

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