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Description

Abstract As a predominant oncogenic driver in non-small cell lung cancer (NSCLC), EGFR frequently undergoes amplification or mutation, with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) like gefitinib and erlotinib constituting frontline therapy for advanced EGFR-mutant cases

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cells were maintained in mTeSR1 (05850, STEMCELL Technologies) and then adapted to 125-ml disposable spinner flasks (89089, VWR) and mixed at a speed of 55 rpm, in a 37 C incubator with 5% CO 2