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assessed the effects of chronic D-pinitol administration (200 mg/kg/day for 18 weeks) in the 5xFAD mouse model of AD

Regulation of neuronal excitability by reactive oxygen species and calcium signaling: Insights into brain aging

[Google Scholar] Muoz M, Villar I, Garca-Erce JA

For mechanism, the antioxidant properties of vitamin E are linked to improvements in serum paraoxonase-1 activity and some metabolic factors in patients with type 2 diabetes, although they did not significantly affect nitrite/nitrate levels