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Gastrointestinal Cytoprotection Originally studied in gastric lesion models, BPC-157 showed protective effects on: Gastric mucosa Intestinal healing Ulcer repair Reference: Sikiric et al., 1993 Gastric mucosal protection PubMed: Experimentally Observed Benefits of BPC 157 Peptides Below are benefits observed in controlled experimental models

Alternative Routes of Administration & the First-Pass Effect There are several reasons for different routes of administration used in clinical medicine ( Table 33 )for convenience (eg, oral), to maximize concentration at the site of action and minimize it elsewhere (eg, topical), to prolong the duration of drug absorption (eg, transdermal), or to avoid the first-pass effect (sublingual or rectal)

Neuroinflammation represents a critical axis of convergence and differentiation