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J Biol Chem 250:14221426 Huang CS, Moore WR, Meister A (1988) On the active site thiol of gamma-glutamylcysteine synthetase: relationships to catalysis, inhibition, and regulation

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Its antioxidant function is mediated by the reductive detoxification of hydrogen peroxide (H 2 O 2 ), reactive nitrogen species (RNS) such as peroxynitrite (ONOO ), and lipid hydroperoxides (L-OOH)

Fatigue and weakness emerged as the symptoms with the strongest influence across the primary and secondary analyses