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In PACs, such targeted trafficking is necessary to position mitochondria near zymogen granules, perinuclear areas, and the PM, thereby supporting stimulussecretion coupling and Ca 2+ homeostasis

These four aspects, which create a dynamic, high-resolution and rich feature dataset for ML applications, are the key to identifying new potential biomarkers, even with low-distinguishing factors or only in combination with any number of other biomarkers