oral melanotic macule on palate Hyperpigmentation of the hard mucosa in a patient with chronic myeloid leukaemia taking imatinib | Maxillofacial Plastic and Reconstructive Surgery Differential Diagnosis of Pigmented Lesions

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However, the primary focus of early endoscopic surveillance is to identify polyps that could lead to intussusception or obstruction rather than for cancer detection, with cancer surveillance becoming a critical component of management as patients age [78]

thus they may be genetically considered as non-classical subtypes of melanoma

This practice aims to create an effect similar to external expansion, thereby increasing the skin around the pigmented nevus, which helps relax the soft tissue and facilitates the excision of more pigmented nevi during subsequent surgeries