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Name: acetyl-l-carnitine reduces depression and improves Frontiers L-Carnitine Supplementation for the Management
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[5] Mechanistic data indicate PAT inhibits NF-B nuclear translocation, the transcription factor governing proinflammatory cytokine and COX-2 gene expression

Senotherapy protects against cisplatin-induced ovarian injury by Removing senescent cells and alleviating DNA damage

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Contraindications: Hypersensitivity Side Effects: CNS Depression (Sedation) & Bradycardia : The most common adverse effects of clonidine are sedation, dry mouth (xerostomia) , fatigue , bradycardia , dizziness, and constipation (Patel and Saadabadi, 2025