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Moreover, the GLP-1 receptor agonist may also be any one of the GLP-1 agonists disclosed in WO 93/19175, WO 96/29342, WO 98/08871 , WO 99/43707, WO 99/43706, WO 99/43341 , WO 99/43708, WO 2005/027978, WO 2005/058954, WO 2005/058958, WO 2006/005667, WO 2006/037810, WO 2006/037811 , WO 2006/097537, WO 2006/097538, WO 2008/023050, WO 2009/030738, WO 2009/030771 , or WO 2009/030774, each of which is incorporated herein by reference

The two peptides work on complementary pathways: CJC-1295 is a GHRH analogue that signals the pituitary gland to increase growth hormone output over time, and Ipamorelin is a selective ghrelin receptor agonist that triggers growth hormone pulses without significantly affecting cortisol or prolactin

Methods Human transcriptomic analysis The public human MASLD patient sample data were obtained from the NCBI Gene Expression Omnibus (GSE162694 and GSE126848) 49