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The work was supported by the Austrian Science Fund FWF The project was supported by the National Laboratories Programme, National Laboratory for Drug Research and Development (PharmaLab), RRF-2.3.1-21-2022-00015

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Animal handling and experimentation were carried out in accordance with the guidelines of the Guide for the Care and Use of Laboratory Animals and were approved by the Laboratory Animal Care and Use Committee of the Shaanxi University of Chinese Medicine