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However, while senescence occurs throughout the lifespan, aging is a progressive decline in time (Zhang et al

Nonsteroidal anti-inflammatory drugs (NSAIDs), as first-line treatments for inflammatory diseases, exert anti-inflammatory and analgesic effects primarily by inhibiting cyclooxygenase (COX) and reducing prostaglandin synthesis ( Since TNF- inhibitors can lessen inflammation and prevent systemic bone loss, they are frequently used in clinical practice as the first-line therapy for rheumatoid arthritis

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This revealed that REW-containing anti-NIP IgG1 has a plasma half-life of 2 weeks (14.2 days), about 2-fold longer than WT IgG1 with the same specificity (7.8 days) (Fig