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Dysregulated lipid metabolism, altered lactate levels, and impaired energy metabolism are key factors that may exacerbate ROS levels

Sun JC, Lanier LL

Indeed, proteinuria is a key biomarker of kidney disease, as it predicts continued progressive functional decline of the kidney or a rapid drop in eGFR to 15 mL/min/1.73 m 2 , which marks end-stage kidney disease [17-19] , a condition that requires dialysis or a kidney transplant for survival