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The amyloid cascade hypothesis, which came into being as a result of the work of Hardy and Higgins in 1992, has almost since then been the dominant purview in the field of AD

Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice

Its lack of iodine lowers the risk of thyroid toxicity, and its shorter half-life, smaller volume of distribution, and reduced tissue accumulation contribute to fewer long-term adverse effects than amiodarone (11)(40)

Some of the most common symptoms are easily confused with general tiredness, diet change, lifestyle change, or weight loss