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doi: 10.1016/j.tjog.2015.07.004 118

An example of a low molecular weight drug is ethanol (Alcohol)

Homozygous and compound heterozygous mutations typically result in severe and early-onset diseases, while heterozygous single-allelic mutants generally result in milder diseases

At the same time, hepcidin levels increase, thereby accelerating the degradation of FPN, closing the iron transport outlet to the blood, and reducing the transport of iron from small intestinal epithelial cells and macrophages to the blood ( In addition, ferroptosis is closely related to iron metabolism under iron overload