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If a compound has a 4-hour half-life, its concentration will be halved every 4 hours

Growth hormone stimulates protein synthesis in bovine skeletal muscle cells without altering insulin-like growth factor-I mRNA expression

Liu J, Kosma V-M, Vnttinen T et al (2002) Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells