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10.1007/s00401-009-0523-2 4 Alegre-AbarrateguiJ.BrimblecombeK

To investigate this aspect, we added BHB to CD4 + T cells in diluted cell culture medium (1:1 with phosphate-buffered saline (PBS)), to more closely resemble the limited availability of nutrients in infection

380 Vorinostat also reduces human immunodeficiency virus (HIV) replication through autophagy activation in infected macrophages without cytotoxicity, 350 supporting the findings of clinical trials for HIV latency reversal (such as NCT01365065, NCT01319383, NCT01933594, and NCT01680094)

High ATP demand, in combination with dysfunctional mitochondria, make these neuron groups more sensitive to degeneration (Wang and Michaelis, 2010)