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Briefly, circulating neutrophils patrol the blood continuously, until they encounter pathogen-derived chemoattractants and inflammatory signals released by immune cells and non-hematopoietic epithelial and endothelial cells in response to tissue injury or infection

[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Maki Y, Horiuchi K, Okamoto T (2022) Fatigue and quality of life among thyroid cancer survivors without persistent or recurrent disease

Berman SM, Voytek B, Mandelkern MA, Hassid BD, Isaacson A, Monterosso J, et al

The authors began with a quality assessment, finding that 14 out of 38 reviewed studies were of poor quality due to failure to control for one or more items on a list of confounding factors that can influence cytokine levels: age, subject activity level, BMI, gender, menstrual cycle stage, comorbid diseases, antidepressant use, or diurnal variation