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Analysis of adenoviral p53 gene therapy clinical trials in recurrent head and neck squamous cell carcinoma

doi: 10.3389/fnins.2025.1614297 Received 09 May 2025 Accepted 16 June 2025 Published 26 June 2025 Volume 19 - 2025 Edited by Katarzyna Stachowicz, Polish Academy of Sciences, Poland Reviewed by Antonio Gambardella, University of Magna Graecia, Italy Qinrui Li, Peking University Peoples Hospital, China Updates Copyright 2025 Shi, Yang, He, Wang, Zheng, Wang, Hao, Feng, Ma, Zhang and Liu

High-histamine foods to reduce or temporarily avoid include: However, a strict low-histamine diet is not intended to be permanent

While some contributing factors to ADA formation are known, the molecular mechanisms of how therapeutic mAbs elicit ADAs are not completely clear