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Moncada et al., 2020

Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro

Similar content being viewed by others Introduction A meticulous transmission between neuronal networks demands the segregation of the central nervous system (CNS) from peripheral organs that is attained via the bloodbrain barrier (BBB)

In this review, we summarize the mechanisms whereby CDDP exerts antineoplastic effects as well as the major determinants of CDDP resistance, laying special emphasis on recent systems biology studies aimed at avoiding or overcoming this crucial clinical issue