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Its role in ferroptosis involves lipid modification, enzyme transport, and stress signalingall of which impact axis progression ( The Golgi influences membrane lipid composition by modifying phospholipids (e.g., adding choline or ethanolamine headgroups) (107)

Additionally, multiobjective optimization methods such as reinforcement learning 271 and Bayesian optimization 272 can help to create formulations that optimize aerosol performance, mucus penetration and cellular uptake at the same time