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Antioxidant nanomaterials in advanced diagnoses and treatments of ischemia reperfusion injuries

Li Y, Liu L, Xing Y, Wang J, Yin W, Huang Y, et al

Accumulating evidence indicated that anesthesia and surgery caused varying degrees of microglial activation, triggering an inflammatory cascade that promoted the synthesis and secretion of inflammatory mediators such as cytokines, eicosanoids, complement factors, excitatory amino acids, reactive oxygen species, and nitric oxide (Hanisch, 2002