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In this study, taking advantage of a panel of in situ hybridization (ISH) probes targeting the marker genes for different stages of OL lineage cells, including Pdgfra, Plp, Mbp, Mog, and especially the recently reported maker gene for newly forming OLs, namely Enpp6 , with the combination of immunofluorescence staining of CC1, SOX10, we provide a temporally detailed dynamic profile of OL lineage cells in the currently most commonly used standardized acute CPZ demyelination model of 5 weeks feeding followed by 4 weeks recovery

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Archived from the original on August 6, 2011

As with l-tyrosine, an alkaline feed containing l-cysteine is used commonly, presenting similar challenges with precipitation and pH spikes