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Dosage timing is often set according to the study model (once daily, split doses, etc.)

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Zhang H, Huang M, Gao L, Lei H (2015) Region-specific cerebral metabolic alterations in streptozotocin-induced type 1 diabetic rats: an in vivo proton magnetic resonance spectroscopy study

Furthermore, the conversion of oxidized glutathione (GSSG) to its reduced form (GSH) by glutathione reductase requires riboflavin in the FAD coenzyme form