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Description

Excess iron accumulation during ferroptosis catalyses the Fenton reaction to produce lipid ROS, which oxidize low-density lipoprotein to form oxidized low-density lipoprotein, leading to lipid deposition, foam cell formation, and endothelial dysfunction

Practical applications

Supports exercise performance and recovery by optimizing levels of nitric oxide (NO) and may decrease lactic acid accumulation in muscles.*

helenium not only inhibits the production of NO and PGE 2 in LPS-activated RAW264.7 murine macrophages, but also attenuates the carrageenan-induced edema in mouse paws, which is a model of acute inflammation (Chun et al., 2019)