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2.3 Cisplatin induces mitochondrial dysfunction When cisplatin enters the mitochondria, it acts directly on the inner mitochondrial membrane, leading to the impairment of the function of the electron transport chain, the reduction of ATP production and the induction of ROS generation (Tan and Song, 2023),these damages further lead to mitochondrial dysfunction, which in turn prompts more ROS production, forming a positive feedback loop (Tan and Vlajkovic, 2023)

How to Safely Use Hyaluronic Acid While on Accutane Application Tips Apply Gently : For Accutane-treated skin, apply a small amount of hyaluronic acid serum on clean, damp skin

Taken together, despite the beneficial effects and few adverse effects of Nrf2 activators, it is necessary to balance their concentration and duration to elucidate their applicability in clinical trials