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Identification of oxidative stress-related genes differentially expressed in Alzheimer's disease and construction of a hub gene-based diagnostic model

In vitro , the Abeta-Cu 2+ complex, in the presence of a reducing agent, reduces oxygen to produce H 2 O 2 , and this involves recycling copper from Cu 2+ to Cu 1+ and back to Cu 2+ along with the oxidation of the reducing agent (Jiang et al., 2010)