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Transgenic Oryza sativa plants demonstrated better tolerance to drought stress than non- transgenic Oryza sativa plants, owing to RNAi-mediated down-regulation of the RACK-1 gene [109]

These effects are mediated through the activation of autophagy-related proteins, such as microtubule-associated protein 1A/1B-light chain 3 (LC3) and Beclin-1 (BECN1), and the reduction of pro-inflammatory markers such as IL-1 and TNF- (Reference Xu, Li and Dai23)

While older techniques like simple suture repair or stoma relocation have high recurrence rates, modern mesh repairs are now the gold standard

Beyond the ferroptosis inhibitors listed above, cell-free therapies utilizing exosomes have emerged as a promising strategy