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Addressing these questions will require time-resolved ubiquitin proteomics and tissue-specific in vivo loss-of-function studies across circadian timepoints to understand how the UPS both encodes and responds to circadian signals at the molecular level

Future of Medical Physics: Real-time MRI-guided proton therapy

doi: 10.3390/ijms21228706 74

The peptide exhibits water solubility and maintains bioactivity across various physiological conditions, though it requires parenteral or intranasal administration due to poor oral bioavailability