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Discontinuation risks cognitive setbacks within 6-12 months

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Vitamin B12 is required for the development, myelination, and function of the central nervous system

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No serious systemic side effects have been documented in peer-reviewed studies at therapeutic doses

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5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT)a metabolic regulator tied to fat storage, NAD depletion, and reduced energy expenditure

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