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Leveraging AlphaFold, the structure of Fks1, the -1,3-glucan synthase targeted by echinocandins, was resolved, revealing resistance-associated mutations, catalytic mechanisms, and the GTP-dependent conformational activation by Rho1 (Hu et al., 2023

Most studies have investigated the isolated compound silymarin or its most active isomer silybin, rather than the plant part in its whole form

Excessive soft tissue growth leads to an enlarged tongue and thickening of the soft palate and pharyngeal tissues, which can cause respiratory stridor in up to 50% of affected cats (15)

Why the Timing of Sleep Matters More Than You Think Most conversations about sleep and skin health focus on quantity: eight hours, seven hours, six hours