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The ability of alpha-lipoic acid to improve energy metabolism and decrease oxidative stress alludes to its ability to support healthy mitochondrial function with age.*

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Many factors that may affect the outcomes of the patients were significantly different in the groups divided by 1-year survival (Table 1), so PSM was used to reduce the bias of the covariables

Here, we first summarize the canonical CoQ 10 biosynthetic pathway and provide a comprehensive overview of both established and emerging CoQ 10 oxidoreductases, such as FSP1, DHODH, SQOR and additional enzymes, emphasizing their biochemical roles in ferroptosis regulation