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These interactions play essential roles in modulating its localization, dimerization, and activation, ensuring that eNOS responds appropriately to cellular and environmental signals (Figure 4)

[DOI] [PMC free article] [PubMed] [Google Scholar] 135.Lauritzen I

Individuals with autosomal recessive familial hyperinsulinism, caused by mutations in either ABCC8 or KCNJ11 (FHI-KATP), tend to be large for gestational age and usually present with severe refractory hypoglycemia in the first 48 hours of life