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Description

High levels of cysteine are toxic in some systems, in part because its amino, carboxyl, and thiol groups are well situated stereochemically to chelate metal ions, which catalyze air oxidation of its thiol group

To investigate potential morphological changes related to senescence, we performed ultrastructural analysis of these organelles in cells treated with T-DXd across three different culture formats: monolayer, mammospheres and matrix-embedded scaffolds