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The insertion at this precise location was conducted using the CRISPR-Cas9 technology for reliable initiation/repression of HDV RNA replication, and production of infectious HDV virions in a cell line that constitutively expresses HBV

Side Effects & Safety Mild GI discomfort most common, usually transient in the first week Slight stimulant effect increased energy/alertness, especially early on Headaches occasional, typically mild and dose-related Mild insomnia if taken too late in the day No human clinical safety data all safety information from preclinical studies and community reports No liver toxicity observed in animal studies at therapeutic doses Unknown drug interactions theoretically could interact with NAD+-dependent pathways Core Supplies for This Protocol The three essentials for running any reconstituted injectable: cold storage, accurate syringes, and metabolic tracking

Pubmed: 22080510 Synthesis Reference: Not Available Material Safety Data Sheet (MSDS) Not Available Links External Links: Resource Link CHEBI ID Not Available HMDB ID HMDB60343 Pubchem Compound ID 0 Kegg ID C14863 ChemSpider ID 10128367 Wikipedia ID Not Available BioCyc ID Not Available Enzymes Protein Details GSH-dependent disulfide bond oxidoreductase General function: Not Available Specific function: Not Available Gene Name: yfcG Locus Tag: PA1033 Molecular weight: 24.5 kDa

Numan M, Sheehan TP (1997) Neuroanatomical circuitry for mammalian maternal behavior