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ISBN 978-0-87893-617-5

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In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion

Future directions for PDCs include integrating Artificial intelligence into conjugate design, developing hybrid systems with other drug-delivery technologies, and advancing sustainable synthesis approaches