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Selenium is involved in the metabolism of hydrogen peroxide and lipid hydroperoxides because it constitutes an integral part of some enzymes, which protect cells from the noxious effects of free radicals formed during oxidation processes ( Taking the advantages of selenium properties, Se NPs could commonly act as an antioxidant factor in normal tissues and cells, which controlled ROS levels to regulate some important signaling events ( Se NPs show anti-inflammatory activities The role of selenium in inflammation has been elucidated, as it acts as a regulatory agent mainly in form of selenoproteins and incorporation ( Vancomycin (VCM) is commonly applied to treat multiresistant Gram-positive bacteria, but its clinical application is limited due to its nephrotoxicity

Acetaldehyde is even more toxic than ethanol due to its high reactivity, forming covalent adducts with proteins [21, 22], phospholipids [23], and nucleic acids [24], thereby altering their biological functions

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2.5 Determination of mineral elements We digested the leaf sample (0.05 g) with concentrated HNO 3 (3 mL)