Sulfites (eg, sodium sulfite) are used as preservatives in food and drugs

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Systemically delivered drugs must cross the BBB, favoring small (under 500 Da) and lipophilic molecules for optimal absorption (Yadav et al., 2015)
TB-500 works through Thymosin Beta-4's actin-sequestering domain to regulate cytoskeletal remodelling and promote endothelial migration, with particular documented activity in cardiac tissue