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Clinically, these mechanisms emphasize the potential value of combining DOX with autophagy inhibitors, lysosomal function modulators, or regulators of lipid raft integrity to overcome resistance

doi:10.5152/iao.2018.4756 Li J, Wu R, Xia B, Wang X, Xue M

Santambrogio, P

Pathogenic genetic variants in one of three genes encoding for amyloid precursor protein ( APP ), presenilin-1 or presenilin-2 lead to a form of the disease known as early-onset familial AD, which accounts for 510% of AD cases 1