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The so-called gatekeeper residue, which usually features a conserved bulky phenylalanine in plant PPOs, is located inside the pocket of the active center and shields CuA 27

Mutation of the tumor suppressor gene p53 in human prostate and bladder cancersinvestigation by temperature gradient gel electrophoresis (TGGE)

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With the homozygous pGSH1-URA3 strain, a ~ 50% increase of GSH cellular content was observed in cultures supplemented with 100 g/ml 5-FOA, and this increase was relatively stable compared to that of the previous heterozygous strain (Figure S4A)