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Endogenous alcohol: Auto-brewery syndrome There is a medical condition, albeit rarely diagnosed, in which an individual experiences the effects of alcohol without actually ingesting alcohol

Proc Natl Acad Sci USA 108:1639816403 Lepore AC, Rauck B, Deje C et al (2008) Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease

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I think thats why it was so easy to point the finger at the river. Large-scale production of lumber, chemicals, and automobiles tainted the waterway during the 19th and 20th centuries