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The result is increased synaptic density and improved neural communication

Fonseca VA, Lavery LA, Thethi TK, Daoud Y, DeSouza C, Ovalle F, Denham DS, Bottiglieri T, Sheehan P, Rosenstock J (2013) Metanx in type 2 diabetes with peripheral neuropathy: a randomized trial

Nat Rev Endocrinol 20 , 447459 (2024)

Elucidating how ceramides exert their effects can enhance pathophysiological understanding of neurodegenerative disorders and constitute potential biological targets for novel drugs and diagnostic and prognostic biomarkers