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As of early 2021, neither medication is approved for any indication in the United States

doi: 10.1371/journal.pone.0276262 19 HallA

*Correspondence: Shaogang Qu, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Lipid peroxidation is the production of polyunsaturated fatty acids (PUFA) as substrates on cell membranes by lipoxygenase or in a non-enzymatic manner 20