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Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling

Class I and Class IV KDACs are nuclear, Class IIb KDACs are cytoplasmic, and Class IIa signaling-responsive KDACs are primarily nuclear but are exported to the cytoplasm upon signal activation

679 Tert-butylhydroquinone (TBHQ), as an Nrf2 activator, has been shown to activate Nrf2-related pathways in a TBI mouse model by combining vanillin acetate and TBHQ, reducing oxidative stress and protecting gray matter in the mouse brain