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Introduction Phyto-estrogens are plant-derived compounds that resemble estrogens in their molecular structure and size, in particular the primary female sex hormone 17-estradiol (E2)

Sulforaphane Sulforaphane , an isothiocyanate, is abundant in various cruciferous vegetables such as broccoli, sprouting broccoli, Brussels sprouts, cabbage, cauliflower, collard greens, kale, kohlrabi, mustard, rutabaga, turnips, bok choy, and Chinese cabbage [152,153]

GLUT, glucose transporter

The elevated level of thyrotropin-releasing hormone in primary hypothyroidism is responsible for the increase in serum prolactin levels and the delayed luteinizing hormone response to the stimulating effect of gonadotropin-releasing hormone, which in turn leads to luteal phase failure in women (124126, 131, 132)