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In this case, we elected ultrasound guidance due to its advantages: realtime visualization of soft tissues and blood vessels (e.g., vertebral artery), radiation-free operation, and dynamic needle placement control

The doses selected for Phase 3 (use our dosing calculator for personalized guidance), based on Phase 2 exposure-response analyses, were 6 mg, 12 mg, and 36 mg for obesity indications and 3 mg, 12 mg, and 36 mg for diabetes indications, reflecting a narrower and somewhat lower dose range than the Phase 2 program's maximum of 45 mg

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