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A significant decrease of these marker proteins was observed in FOXO4-DRI treated group compared with the control group (Figure 2D)

Nevertheless, current nucleic acid methods exhibit representatively the restricted sensitivity for living cell imaging and intracellular analysis 29,30,31

The molecular structure of tight junctions of the bloodbrain barrier proper in the adult brain has been extensively studied and reviewed (e.g., Abbott et al., 2010)