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Then after another half-life (6 hours) the plasma concentration will fall to 3 mg/liter

The process began on day 2 or day 3 of the menstrual cycle with daily oral estradiol doses of 68 mg (Ediol, Synmosa Biopharma Corporation, Hsinchu County, Taiwan) in combination with estradiol gel (Oestrogel gel, Besins, Drogenbos, Belgium)