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Description

Cytoprotective preconditioning of osteoblast-like cells with N-Acetyl-L-Cysteine for bone regeneration in cell therapy

403 The CpG motif is prevalent in bacteria, and the CpG motif also recognizes plasmacytoid dendritic cells (pDC) expressing TLR9 that produce pro-inflammatory cytokines, induce Th1-like immune activation patterns and activate their migration, while CpG-A oligodeoxynucleotides (ODN) induces extremely high levels of IFN- production and CpG-B ODN induces activation of murine bone marrow-derived DCs to secrete IL-12 and IL-6